人急性骨髓白血病細胞KG-1A

細胞名稱

人急性骨髓白血病細胞KG-1A

貨物編碼

BFN60810771

產品規格

T25培養瓶x1

1.5ml凍存管x2

細胞數量

1x10^6

1x10^6

保存溫度

37℃

-198℃

運輸方式

常溫保溫運輸

干冰運輸

安全等級

1

用途限制

僅供科研   3類

培養體系

DMEM高糖（hyclone SH3022.01）+10%FBS+1%三抗

培養溫度

37℃

二氧化碳濃度

5%

簡介

人急性骨髓白血病細胞KG-1A取自59歲男性供體

注釋

Doubling time: ~45 hours (CLS); ~50 hours (DSMZ).

Omics: Transcriptome analysis.

Derived from sampling site: Bone marrow.

基因突變

FGFR1OP2-FGFR1 gene fusion (from parent cell line).

NRAS p.Gly12Asp (c.35G>A) (ClinVar=VCV000039648) (from parent cell line).

Homozygous for TP53 c.672+1G>A; splice donor mutation (from parent cell line).

HLA信息

/

STR信息

Amelogenin        X,Y

CSF1PO        7

D2S1338        20,23

D3S1358        15,16

D5S818        13

D7S820        8,10

D8S1179        13,14 (CCRID; CLS; PubMed=11416159; PubMed=25877200)

14 (COG)

D13S317        11,12

D16S539        10,11

D18S51        10.2,18

D19S433        11,16.2 (COG)

16.2 (PubMed=25877200)

D21S11        28,29

FGA        22

Penta D        8,9

Penta E        7,13

TH01        7,8

TPOX        7,9 (ATCC; CCRID; CLS; COG; DSMZ; ECACC; RCB; TKG)

7 (PubMed=25877200)

vWA        14,19

參考文獻

PubMed=6967340; DOI=10.1182ood.V56.2.265.265

Koeffler H.P., Billing R., Lusis A.J., Sparkes R.S., Golde D.W.

An undifferentiated variant derived from the human acute myelogenous leukemia cell line (KG-1).

Blood 56:265-273(1980)

PubMed=3094604; DOI=10.1182ood.V68.5.1101.1101

Furley A.J.W., Reeves B.R., Mizutani S., Altass L.J., Watt S.M., Jacob M.C., van den Elsen P., Terhorst C., Greaves M.F.

Divergent molecular phenotypes of KG1 and KG1a myeloid cell lines.

Blood 68:1101-1107(1986)

PubMed=8558913

Morita S., Tsuchiya S., Fujie H., Itano M., Ohashi Y., Minegishi M., Imaizumi M., Endo M., Takano N., Konno T.

Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.

Leukemia 10:102-105(1996)

DOI=10.1016/B978-0-12-221970-2.50457-5

Drexler H.G.

The leukemia-lymphoma cell line factsbook.

(In) ISBN 9780122219702; pp.1-733; Academic Press; London (2001)